Short description on all the CILTEP Ingredients

One of the main ingredients in CILTEP is premium quality extract from the leaves of the artichoke plant. Artichoke extract has been used since ancient times for its multiple health benefits; long before its nootropic properties became known. The main bioactive phytochemicals in artichoke extract are caffeylquinic acids, which include luteolin.  The artichoke extract used in CILTEP is standardised to contain 5% caffeylquinic acids.The cognition and memory enhancing properties of artichoke extract come from the fact that luteolin is an inhibitor of phosphodiesterase 4 (PDE-4). It therefore inhibits the enzyme that is responsible for the breakdown of cyclic AMP (cAMP). cAMP is a potent second messenger that transduces the signals of multiple hormones and neurotransmitters from outside the cell to the cytoplasm and the nucleus.Read more..

How Ciltep nootropic formula induce long-term potentiation 

Natural Stacks’ nootropic formula, CILTEP, aims to chemically induce long-term potentiation by increasing the intracellular levels of the second messenger cyclic AMP (cAMP) through a two-pronged approach. CILTEP contains foreskolin, in the form of Coleus forskohlii extract, which stimulates the synthesis of cAMP by activating the enzyme adenylyl cyclase. On the other hand, the lutoelin from artichoke extract in CILTEP, prevents the breakdown of cAMP by inhibiting the enzyme phosphodiesterase 4 (PDE4). The elevated levels of cAMP induce long-term potentiation, the brain’s endogenous mechanism for storing memories. The effect is enhanced cognition, improved ability to learn, and better memory.Read more..